Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort.
Constance J.H.C.M. van Laarhoven, Jessica van Setten, Joost A. van Herwaarden, Gerard Pasterkamp, Dominique P.V. de Kleijn, Gert Jan de Borst, Sander W. van der Laan
The paper investigates the association between genetic risk variants and clinical features of abdominal aortic aneurysms using a biobank cohort, finding a weak polygenic correlation with aneurysm diameter but no clear individual variant associations.
Scientific Reports · Dec 27, 2019Peer-reviewedGenetics