Author

Frank V. Marcoline

University of California, San FranciscoORCID 0000-0002-8842-5470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Christian J. PetersiD· 1 shared Christina Alexandra StephensiD· 1 shared Michael GrabeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Christian J. PetersORCID

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1 paper

Recent·Most cited

BiophysicsThe Journal of General PhysiologyPeer-reviewedMay 28, 2026

Conformational changes upon pore blocker removal reveal conductive states of TMEM16A

Christina Alexandra Stephens, Frank V. Marcoline, Christian J. Peters, Michael Grabe

The paper uses molecular dynamics simulations and electrophysiology to study conformational changes in TMEM16A upon inhibitor removal, revealing conductive and non-conductive states and mechanisms of Ca2+-dependent gating.

1 citation

protein structuremechanistic / dynamical model

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