Interactions between the picornavirus 3C(D) main protease and RNA induce liquid-liquid phase separation
Somnath Mondal, Saumyak Mukherjee, Kevin E. W. Namitz, Neela H. Yennawar, David D. Boehr
This study shows that the picornavirus 3C protease binds RNA and induces liquid-liquid phase separation, which may have implications for viral replication and stress granule dynamics.
bioRxiv · Apr 14, 2025 · PreprintBiophysics