Neela H. Yennawar

This study identifies a fold switch in ONNV nsP4 that regulates its conformation, RNA binding, and polymerase activity through proteolytic cleavage and fold switching.

This paper develops a computational pipeline to identify conserved antiviral target sites in alphaviruses using AI-driven methods, validating potential drug targets through mutagenesis.

The paper identifies and characterizes shifted GU wobble pairs in RNA through cheminformatics and experimental validation, showing alternative protonation states may enhance RNA function.

This study shows that the picornavirus 3C protease binds RNA and induces liquid-liquid phase separation, which may have implications for viral replication and stress granule dynamics.

This study identifies a poliovirus nonstructural protein 3CD with an LIR motif critical for non-lytic spread via autophagosome incorporation and trafficking.

This study characterizes the RNA-binding properties of a disordered protein, SERF, and shows that binding to RNA causes modest global compaction without inducing structural changes in either molecule.

This study characterizes recombinant human lactoferrin produced in yeast, confirming its sequence, purity, glycosylation, structure, and thermal stability similar to native human milk lactoferrin.