Identification of the keystone species in non-alcoholic fatty liver disease by causal inference and dynamic intervention modeling
Dingfeng Wu, Na Jiao, Ruixin Zhu, Yida Zhang, Wenxing Gao, Sa Fang, Yichen Li, Sijing Cheng, Chuan Tian, Ping Lan, Rohit Seth Loomba, Lixin Zhu
The paper identifies eight keystone species in NAFLD gut microbiota using causal inference and dynamic intervention modeling, which can restore microbial composition toward a normal state.
bioRxiv · Aug 6, 2020 · PreprintBioinformatics