PhOxi-seq detects enzyme-dependent m2G in multiple RNA types
Marie Klimontova, Kimberley Chung Kim Chung, Han Zhang, Tony Kouzarides, Andrew J. Bannister, Ryan Hili
The paper introduces an optimized PhOxi-seq workflow and bioinformatic pipeline to detect enzyme-dependent m2G modifications across multiple RNA types, generating a database of high-confidence THUMPD3-dependent m2G sites in human cancer cells.
ACS Chemical Biology · Nov 29, 2024Peer-reviewedBiochemistry