Author

Sara Shanaj

Hospital for Special SurgeryORCID 0000-0002-8945-7626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aparna NathaniD· 1 shared Fan ZhangiD· 1 shared Ilya KorsunskyiD· 1 shared Jessica I. BeynoriD· 1 shared Joseph MearsiD· 1 shared Laura T. DonliniD· 1 shared Lorien ShakibiD· 1 shared Soumya RaychaudhuriiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Aparna NathanORCID

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1 paper

Recent·Most cited

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation

Fan Zhang, Joseph Mears, Lorien Shakib, Jessica I. Beynor, Sara Shanaj, Ilya Korsunsky, Aparna Nathan, Laura T. Donlin, Soumya Raychaudhuri

The paper identifies a common inflammatory macrophage phenotype across severe COVID-19 and other inflammatory diseases, driven by IFN-γ and TNF-α, and suggests potential therapeutic targets.

Genome Medicine · Apr 20, 2021Peer-reviewedGenomics