RNA Polymerase II Degradation Triggered by DNA Repair Occurs In Trans and Independently of how the Lesion is Recognised
Ramveer Choudhary, Juan Cristobal Muñoz, Inés Beckerman, Giulia Bastianello, León Alberto Bouvier, Marco Foiani, Manuel Javier Muñoz
The paper shows that RPB1 degradation by the ubiquitin-proteasome system occurs in trans and is controlled by NER activity, regardless of lesion recognition mechanism.
bioRxiv · Aug 30, 2024 · PreprintMolecular Biology