Iron dysregulation in mice engineered with a mutation associated with stuttering
Marissa Millwater, Camryn Bragg, Devin M. Bishop, Afuh Adeck, Rahul Chowdary Karuturi, Maximillian Weinhold, Praveen P.N. Rao, Ruli Zhang, Shahriar SheikhBahaei
This study shows that a Gnptab mutation in mice leads to iron accumulation in the basal ganglia, which is linked to vocalization symptoms that improve with iron chelation.
bioRxiv · Jul 30, 2025 · PreprintCell Biology