Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry
Aleksandr S. Taraskin, Konstantin K. Semenov, Aleksandr V. Protasov, Alexey A. Lozhkov, Alexander A. Tyulin, Aram A. Shaldzhyan, Edward Smith Ramsay, O. A. Mirgorodskaya, Sergey A. Klotchenko, Yana A. Zabrodskaya
This paper describes a method to measure A2M concentration in human serum using MALDI mass spectrometry by analyzing the release of a specific peptide after trypsin interaction.
Biochimie · Mar 18, 2021Peer-reviewedMolecular Biology