Yana A. Zabrodskaya

Spontaneous formation of different forms of alpha-synuclein fibrils from a recombinant protein

This study shows that recombinant alpha-synuclein can form different fibril types under the same conditions, and these fibrils can act as seeds to produce similar fibrils.

Stick of Sticks: Structural Features of the Amyloidogenic Peptide-DNA Complex

This study investigates how an amyloidogenic peptide binds to DNA, showing its structural interactions and effects on DNA function.

Mangiferin As A Potential Inhibitor Of Transthyretin Fibrillogenesis

The paper predicts and validates that mangiferin inhibits transthyretin fibrillogenesis using in silico docking and in vitro assays.

Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro

This study compares the efficiency of cell-penetrating peptides and cationic liposomes for delivering anti-BCR-ABL siRNA to inhibit CML cell growth in vitro.

Old Dog, New Tricks: Influenza A Virus NS1 and In Vitro Fibrillogenesis

This study shows that influenza A NS1 protein can form amyloid-like fibrils in vitro, with structural changes detected by proteolysis and mass spectrometry.

Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry

This paper describes a method to measure A2M concentration in human serum using MALDI mass spectrometry by analyzing the release of a specific peptide after trypsin interaction.