B cell/adipocyte crosstalk drives pro-fibrotic macrophage migration and polarisation in Crohn`s disease-associated, inflamed adipose tissue
Marie Christine Goess, Julia M. Heinze, Julian I. Hofmann, Annalisa Buck, Iana Gadjalova, Marie-Christin Weber, Sandra Stephanie Ring, Joerg Martin Buescher, Matteo Villa, Philipp‐Alexander Neumann, Jürgen Ruland, Selina Jessica Keppler
The paper shows B cell/adipocyte interactions drive pro-fibrotic macrophage accumulation and polarization in inflamed adipose tissue in Crohn's disease.
bioRxiv · Jul 11, 2025 · PreprintImmunology