Author

Jürgen Ruland

German Cancer Research CenterORCID 0000-0002-8381-3597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alix SchwarziD· 1 shared André GessneriD· 1 shared Andreas HiergeistiD· 1 shared Andreas MamilosiD· 1 shared Annalisa Buck· 1 shared Chiara Suriano· 1 shared Christian SchmidliD· 1 shared Claudia GebhardiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Alix SchwarzORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A microbial metabolite protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration

Sascha Göttert, Erik Thiele Orberg, Kaiji Fan, Paul Heinrich, Diana M. Matthe, Omer Khalid, Lena Klostermeier, Chiara Suriano, Nicholas Strieder, Claudia Gebhard, Eva Vonbrunn, Andreas Mamilos, Daniela D. Hirsch, Elisabeth Meedt, Karin Kleigrewe, , Hendrik Poeck

This study identifies desaminotyrosine (DAT) as a microbial metabolite that protects against graft-versus-host disease by promoting intestinal regeneration and modulating immune responses.

Nature Communications · Oct 20, 2025Peer-reviewedImmunology

B cell/adipocyte crosstalk drives pro-fibrotic macrophage migration and polarisation in Crohn`s disease-associated, inflamed adipose tissue

Marie Christine Goess, Julia M. Heinze, Julian I. Hofmann, Annalisa Buck, Iana Gadjalova, Marie-Christin Weber, Sandra Stephanie Ring, Joerg Martin Buescher, Matteo Villa, Philipp‐Alexander Neumann, Jürgen Ruland, Selina Jessica Keppler

The paper shows B cell/adipocyte interactions drive pro-fibrotic macrophage accumulation and polarization in inflamed adipose tissue in Crohn's disease.

bioRxiv · Jul 11, 2025 · PreprintImmunology