Paweł Zawadzki

The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.

The paper describes the creation of a national database of Polish genomic variant allele frequencies using 1,079 whole genomes, identifying rare variants and confirming allele frequencies for known pathogenic variants.

The paper develops an AI-driven, ploidy-corrected method using whole genome sequencing to accurately determine HER2 status in breast cancer patients.

This study evaluates the accuracy of somatic variant detection workflows in WGS experiments using real and synthetic data, finding DRAGEN excels in sensitivity while CGP-WGS performs better in precision.