Author

Chen‐Yu Lee

Johns Hopkins UniversityORCID 0000-0002-9041-7023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra Ida CeliaiD· 2 shared Andrea FavaiD· 2 shared Avi Z. RosenbergiD· 2 shared Jill P. BuyoniD· 2 shared Michelle PetriiD· 2 shared Peter IzmirlyiD· 2 shared Accelerating Medicines Partnership: RA/SLE Network· 1 shared Alexandre Cammarata-MouchtourisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Alessandra Ida CeliaORCID

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2 papers

Recent·Most cited

Serial Immunohistochemistry for High-Dimensional Single-Cell Spatial Analysis of Human Kidney Biopsies

X. J. Yang, Matthew Caleb Marlin, Alessandra Ida Celia, Chen‐Yu Lee, Alexandre Cammarata-Mouchtouris, Tayte Stephens, Majood Haddad, Liz Bradshaw, Daksh Saksena, Jill P. Buyon, Peter Izmirly, Chaim Putterman, Diane L. Kamen, Michelle Petri, Accelerating Medicines Partnership: RA/SLE Network, , Avi Z. Rosenberg

This paper develops a serial immunohistochemistry method to detect multiple antigens on kidney biopsy slides, enabling high-dimensional single-cell spatial analysis.

bioRxiv · Aug 12, 2026 · PreprintPathology

Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus Nephritis

Silvia Malvica, Paride Fenaroli, Chen‐Yu Lee, Sarah Louis, Alessandra Ida Celia, Serena Maria Bagnasco, Xiaoping Yang, Daniel Salvetti, Jeffrey B. Hodgin, Michael H Belmont, Peter Izmirly, Jill P. Buyon, Laurence S. Magder, Michelle Petri, The Accelerating Medicines Partnership: RA/SLE Network, , Andrea Fava

This study examines inflammation in fibrotic areas of kidney biopsies from lupus nephritis patients and finds that the degree of inflammation correlates with future kidney function decline.

Lupus Science & Medicine · Jul 1, 2025Peer-reviewedImmunology