Xiaoping Yang

This study identifies DNA damage-driven senescence and ZBP1-cGAS-STING signaling as conserved mechanisms linking cardiovascular-kidney-metabolic comorbidities to HFpEF.

This study characterizes an ALMS1 knockout rat model, showing it develops metabolic syndrome with hypertension, obesity, and hyperleptinemia, revealing ALMS1's role in metabolic regulation and its sex- and age-dependent effects.

This study examines inflammation in fibrotic areas of kidney biopsies from lupus nephritis patients and finds that the degree of inflammation correlates with future kidney function decline.

This study shows that NAD+ supplementation protects against CKD in Alport syndrome by restoring FAO in proximal tubule cells and reveals sex differences in transcriptional responses.

The paper integrates proteomic and genomic data from skeletal muscle myocytes to identify gene and protein expression differences between slow and fast-twitch fiber types.