Alberto J. Rico

The paper shows that mole rats accumulate neuromelanin with age, suggesting that long-lived rodents develop this pigment, while short-lived rodents like mice and rats do not reach detectable levels due to their shorter lifespans.

This study investigates tier-specific vulnerability of dopaminergic neurons in non-human primates by analyzing Lewy body distribution and neuromelanin levels in different brain regions.

The paper introduces a novel mouse model of Parkinson's disease using a modified viral vector to induce pigmentation and pathological features associated with the disease.

This study develops a non-human primate model of disseminated synucleinopathy using AAV to induce alpha-synucleinopathy and characterizes its distribution and impact.

This study shows that neuromelanin accumulation in non-human primates leads to synucleinopathy and dopaminergic neuron degeneration, mimicking Parkinson's disease pathology.