Author

Goiaz Ariznabarreta

Instituto de Salud Carlos IIIORCID 0000-0002-8975-8971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:non-human primate· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Alberto J. RicoiD· 5 shared José Luis LanciegoiD· 5 shared Julia ChocarroiD· 5 shared Elena Lorenzo-RamosiD· 3 shared Mario M. IlarduyaiD· 3 shared Adriana HonrubiaiD· 2 shared Cristina CanalesiD· 2 shared Elvira RodaiD· 2 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersNeuroscience

Alberto J. RicoORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

When longevity becomes chemistry: Why rodent brains lack neuromelanin

Cristina Canales, Mario M. Ilarduya, Julia Chocarro, Alberto J. Rico, Goiaz Ariznabarreta, Elena Lorenzo-Ramos, Dolores Carbonell, Radim Šumbera, Jan Okrouhlík, Daniel Ruiz‐Molina, José Luis Lanciego

The paper shows that mole rats accumulate neuromelanin with age, suggesting that long-lived rodents develop this pigment, while short-lived rodents like mice and rats do not reach detectable levels due to their shorter lifespans.

bioRxiv · Oct 16, 2026 · PreprintNeuroscience

Tier-specific location of Lewy body pathology and related neuromelanin levels drive dopaminergic cell vulnerability in pigmented non-human primates

Julia Chocarro, Alberto J. Rico, Goiaz Ariznabarreta, Elena Lorenzo-Ramos, Mario M. Ilarduya, Cristina Canales, Adriana Leon-Villares, Javier Blesa, Jose Angel Obeso, José Luis Lanciego

This study investigates tier-specific vulnerability of dopaminergic neurons in non-human primates by analyzing Lewy body distribution and neuromelanin levels in different brain regions.

Neurobiology of Disease · Jun 28, 2026Peer-reviewedNeuroscience

Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease

Julia Chocarro, Sergio Maraña, María Espelosin, Alberto J. Rico, Goiaz Ariznabarreta, Elena Lorenzo-Ramos, Mario M. Ilarduya, Rubén Hernández-Alcoceba, Miquel Chillón, Miquel Vila, Jeffrey H. Kordower, Anthony H.V. Schapira, Ana García‐Osta, Mar Cuadrado‐Tejedor, José Luis Lanciego

The paper introduces a novel mouse model of Parkinson's disease using a modified viral vector to induce pigmentation and pathological features associated with the disease.

npj Parkinson s Disease · Feb 11, 2026Peer-reviewedNeuroscience

Development And Characterization Of A Non-Human Primate Model Of Disseminated Synucleinopathy

Alberto J. Rico, Almudena Corcho, Julia Chocarro, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, Patricia Arnaiz, José Luis Lanciego

This study develops a non-human primate model of disseminated synucleinopathy using AAV to induce alpha-synucleinopathy and characterizes its distribution and impact.

Frontiers in Neuroanatomy · Mar 27, 2024Peer-reviewedNeuroscience

Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates

Julia Chocarro, Alberto J. Rico, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, María Collantes, Iván Peñuelas, Alfonso Vázquez, Ana Isabel Rodriguez-Perez, José Luis Labandeira-García, Miquel Vila, José Luis Lanciego

This study shows that neuromelanin accumulation in non-human primates leads to synucleinopathy and dopaminergic neuron degeneration, mimicking Parkinson's disease pathology.

Brain · Sep 28, 2023Peer-reviewedNeuroscience