Author

Seth J. Welsh

University of IowaORCID 0000-0002-9073-2162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Angela F.M. Nelson· 1 shared Anna R Carmen· 1 shared Carla NesteriD· 1 shared Christoph Q. SchmidtiD· 1 shared Christopher T. CulekiD· 1 shared Cobey J. H. Donelson· 1 shared Dingwu Shao· 1 shared Héctor Martín MerineroiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Angela F.M. Nelson

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1 paper

Recent·Most cited

Monoclonal nephritic factors reveal insights into C3 convertase dynamics and dysregulation

Seth J. Welsh, Christopher T. Culek, Zhen Xu, Héctor Martín Merinero, Jannik Sichau, William D. Walls, Renee X. Goodfellow, Dingwu Shao, Cobey J. H. Donelson, Kameron Kruger, Sarah Roberts, Nicole C. Meyer, Angela F.M. Nelson, Anna R Carmen, Sydney S. Jellison, , Richard J. Smith

The paper identifies monoclonal C3- and C5-nephritic factors, reveals their structural interactions with convertases, and explains their dual role in activating or inhibiting convertase activity.

bioRxiv · Jun 12, 2026 · PreprintImmunology