Author

Amanda K. Shilton

Rockefeller UniversityORCID 0000-0002-9083-8696Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amir BrivanlouiD· 1 shared Bernardo Sgarbi ReisiD· 1 shared Luciano A. MarraffiniiD· 1 shared Naama AviramiD· 1 shared Nia G. LyniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

Amir BrivanlouORCID

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1 paper

Recent·Most cited

The Cas10 nuclease activity relieves host dormancy to facilitate spacer acquisition and retention during type III-A CRISPR immunity

Naama Aviram, Amanda K. Shilton, Nia G. Lyn, Bernardo Sgarbi Reis, Amir Brivanlou, Luciano A. Marraffini

This study shows that the Cas10 nuclease activity in type III-A CRISPR-Cas systems relieves host dormancy to enable spacer acquisition and retention, enhancing broad-spectrum immunity.

Cell Host & Microbe · Dec 1, 2024Peer-reviewedMicrobiology