GeneticsbioRxivPreprint
Evolutionary rewiring of the DNM2 proline-rich domain drives lineage-specific constraints in erythropoiesis
Thomas Arbogast, Peggy Kirstetter, Christine Kretz…·Jocelyn Laporte
This study shows that human DNM2 causes erythropoiesis defects in mice due to rewiring of the proline-rich domain interactome, highlighting the importance of regulatory domains in tissue-specific function.
DOI 10.64898/2026.03.20.713161