NeurosciencebioRxivPreprint
SARS-CoV-2 spike protein induces long-term TLR4-mediated synapse and cognitive loss recapitulating Post-COVID syndrome
Fabrícia Lima Fontes-Dantas, Gabriel Gripp Fernandes, Elisa Gouvea Gutman…·Cláudia Pinto Figueiredo
The paper shows that SARS-CoV-2 spike protein causes long-term cognitive and synaptic damage in mice, and a TLR4 genetic variant is linked to worse cognitive outcomes in post-COVID patients.
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