Author

Ashlynn G Bruder

Vanderbilt UniversityORCID 0000-0002-9115-2063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Megan G. BehringeriD· 1 shared Nathan Fiedeldey· 1 shared Sarah B. WorthaniD· 1 shared Zeer Cen· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperEvolutionary Biology

Megan G. BehringerORCID

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1 paper

Recent·Most cited

Environment-dependent epistasis shapes adaptation to fluctuating resources.

Ashlynn G Bruder, Nathan Fiedeldey, Sarah B. Worthan, Zeer Cen, Megan G. Behringer

This study shows how fluctuating environments shape genetic interactions in E. coli by selecting for mutations in transport genes that exhibit environment-dependent epistasis and improve fitness across feast and famine conditions.

bioRxiv · Aug 4, 2026 · PreprintEvolutionary Biology