Author

Adam J.H. Quek

CSL (Australia)ORCID 0000-0002-9120-2681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrew D. Nash· 1 shared Con PanousisiD· 1 shared Eugene A. KappiD· 1 shared Ieva DrulyteiD· 1 shared Matthias PelzingiD· 1 shared Michael J. Wilson· 1 shared Rajesh GhaiiD· 1 shared Saw Yen OwiD· 1 shared

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2024-2024 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Andrew D. Nash

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1 paper

Recent·Most cited

BiochemistryStructurePeer-reviewedJul 25, 2024

Structural basis for inhibition of βFXIIa by garadacimab

Ieva Drulyte, Rajesh Ghai, Saw Yen Ow…·Matthias Pelzing

This paper presents a high-resolution cryo-EM structure of garadacimab Fab bound to βFXIIa, revealing its unique binding mechanism and insights into FXII inhibition in HAE.

17 citationstop 4%

humanprotein structure

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