SLIDE-VIP: a comprehensive, cell line- and patient-based framework for synthetic lethality prediction in DNA damage repair, chromatin remodeling and cell cycle
Magda Markowska, Magdalena A. Budzinska, Anna M. L. Coenen-Stass, Senbai Kang, Ewa Kizling, Krzysztof Kolmus, Krzysztof Koras, Eike Staub, Ewa Szczurek
SLIDE-VIP identifies synthetic lethal gene pairs in DNA damage repair, chromatin remodeling, and cell cycle using multi-omics data and eight statistical tests, reducing candidate pairs by 250-fold.
bioRxiv · Jul 7, 2022 · PreprintBioinformatics