Senbai Kang

The paper identifies eicosanoid-enriched follicular microenvironments in HIV-infected individuals on antiretroviral therapy that may influence antibody responses and viral reservoir persistence.

The paper evaluates Xenium spatial transcriptomics performance, identifies technical limitations, and introduces SPLIT to improve signal purity and cell-type resolution.

DelSIEVE infers cell phylogeny and variants from scDNA-seq data, improving detection of deletions and evolutionary events compared to existing methods.

The paper compares three transcriptomic methods on FFPE tumor samples to assess their ability to detect inter- and intra-patient heterogeneity.

SIEVE jointly infers somatic variants and cell phylogeny from scDNA-seq data, showing improved accuracy in both tasks compared to existing methods.

SLIDE-VIP identifies synthetic lethal gene pairs in DNA damage repair, chromatin remodeling, and cell cycle using multi-omics data and eight statistical tests, reducing candidate pairs by 250-fold.