ImmunologyPLoS ONEPeer-reviewed
HIV-1 controllers possess a unique CD8+ T-cell activation phenotype and loss of control is associated with increased expression of exhaustion markers
Amber D. Jones, Zachary Capriotti, Erin Santos…·Zachary A. Klase
The paper examines CD8+ T-cell exhaustion in HIV-1 controllers and finds that loss of control correlates with increased exhaustion markers, which can be reversed by immune checkpoint blockade.
6 citations