Author

Laure Piechaczyk

Oslo University HospitalORCID 0000-0002-9165-0337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Aram Nikolai AnderseniD· 2 shared Jorrit M. EnserinkiD· 2 shared Andrea LenartovaiD· 1 shared Andrea M. Brodersen· 1 shared Dagim Shiferaw TadeleiD· 1 shared Julia Fredriksen· 1 shared Lizet Baken· 1 shared Manuela ZucknickiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Aram Nikolai AndersenORCID

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2 papers

Recent·Most cited

Perturbational fitness analysis of CRISPR screens uncovers information-theoretic relation between gene function and selection

Aram Nikolai Andersen, Nathalia Chica, Laure Piechaczyk, Sigve Nakken, Manuela Zucknick, Jorrit M. Enserink

This study uses information theory to analyze CRISPR screens and quantifies gene function through geometric measures of selection dynamics and environmental perturbations.

bioRxiv · Apr 29, 2025 · PreprintSystems Biology

Clinical Forecasting using Ex Vivo Drug Sensitivity Profiling of Acute Myeloid Leukemia

Aram Nikolai Andersen, Andrea M. Brodersen, Pilar Ayuda Durán, Laure Piechaczyk, Dagim Shiferaw Tadele, Lizet Baken, Julia Fredriksen, Mia Stoksflod, Andrea Lenartova, Yngvar Fløisand, Jorrit M. Enserink

This study evaluates ex vivo drug sensitivity profiling in AML patients to predict survival and chemotherapy response, showing its robustness in mapping treatment response signatures.

bioRxiv · Oct 11, 2022 · PreprintBioinformatics