Michael R. Vella

Development and testing of a novel Killer-Rescue self-limiting gene drive system in Drosophila melanogaster

The paper develops and tests a self-limiting gene drive system in Drosophila melanogaster using Gal4/UAS and Gal80, showing it can drive rescue genes through populations.

Mathematical modeling of genetic pest management through female-specific lethality: Is one locus better than two?

This paper compares single- and two-construct female-killing genetic strategies for pest suppression using a population genetics model, finding that two-construct strains can lead to stronger suppression with smaller releases.

Invasion and migration of spatially self-limiting gene drives: a comparative analysis

This paper compares three spatially self-limiting gene drive systems using a population genetics model, finding differences in their efficiency, localization, and risk of unintended spread.