This study synthesizes silver nanoparticles from Guibourtia tessmannii bark extract and shows they have strong anti-inflammatory and anticoagulant effects in vitro and in vivo.

bioRxiv · Jul 6, 2026 · PreprintPharmacology & Toxicology

Magnesium hydroxide nanoneedles derived from Anthocleista schweinfurthii Gilg (Loganiaceae) support mesenchymal stromal cell proliferation and wound healing

François Eya’ane Meva, Ana Rita Pereira, Sandrine Elodie Ngnihamye, Armel Florian Tchangou Njiemou, Agnes Antoinette Ntoumba, Jean Baptiste Hzounda Fokou, Thi Hai Yen Beglau, Marcus N. A. Fetzer, Marilyn Kaul, Bianca Schlierf, Ulrich Armel Mintang Fongang, Philippe Belle Ebanda Kedi, Simone Véronique Fannang, Marietta Herrmann, Christoph Janiak

This study shows that Mg(OH)2 nanoneedles from Anthocleista schweinfurthii promote mesenchymal stromal cell proliferation and enhance wound healing in rats.

Journal of Inorganic and Organometallic Polymers and Materials · Aug 14, 2025Peer-reviewedPharmacology & Toxicology

Anti-inflammatory assessment of zinc oxide nanoparticles mediated Aframomum citratum (C. Pereira) K. Schum (Zingiberaceae) in Wistar rats

François Eya’ane Meva, Denise Murielle Nga Essama, Edwige Laure Nguemfo, Hans-Denis Bamal, Agnes Antoinette Ntoumba, Philippe Belle Ebanda Kedi, Thi Hai Yen Beglau, Tako Djimefo Alex Kevin, Annie Guilaine Djuidje, Geordamie Chimi Tchatchouang, Chick Christian Nanga, Gildas Fonye Nyuyfoni, Armel Florian Tchangou Njiemou, Madeleine Ines Danielle Evouna, Armel Ulrich Mintang Fongang, Christoph Janiak

This study synthesizes zinc oxide nanoparticles from Aframomum citratum seed extract and evaluates their anti-inflammatory properties and safety in rats.

Journal of Inorganic and Organometallic Polymers and Materials · May 1, 2025Peer-reviewedPharmacology & Toxicology

Cylicodiscus gabunensis (FABACEAE) aqueous stem bark extract mediated silver nanoparticle enhance anti-inflammation on Wistar rats

François Eya’ane Meva, Pamela Ngadie Mponge, Juliette Koubé, Gildas Fonye Nyuyfoni, Jean Baptiste Hzounda Fokou, Agnes Antoinette Ntoumba, Thi Hai Yen Beglau, Tako Djimefo Alex Kevin, Annie Guilaine Djuidje, Geordamie Chimi Tchatchouang, Ariane Laure Wounang, Madeleine Ines Danielle Evouna, Maeva Jenna Chameni Nkouankam, Yolaine Pamela Dada Youte, Hassana Moussa Ndotti, , Christoph Janiak

This paper synthesizes silver nanoparticles from Cylicodiscus gabunensis stem bark extract and evaluates their anti-inflammatory effects in vitro and in vivo on Wistar rats.

bioRxiv · Dec 15, 2024 · PreprintPharmacology & Toxicology

Chitosan nanocapsules with Alstonia boonei extract modulate the immune system in Wistar rats

Gildas Fonye Nyuyfoni, François Eya’ane Meva, Ninpa Kuissi Chris Rosaire, Hans-Denis Bamal, Simone Véronique Fannang, Thi Hai Yen Beglau, N. A. Fetzer Marcus, Agnes Antoinette Ntoumba, Edwige Laure Nguemfo, Hzounda Fokou Jean Batiste, Annie Guilaine Djuidje, Augustine Nkojap Kuinze, Tako Djimefo Alex Kevin, Tchangou Njiemou Armel Florian, Evouna Danielle Ines Madeleine, , Janiak Christoph

This paper develops chitosan nanocapsules with Alstonia boonei extract and shows they prevent dexamethasone-induced immunosuppression in rats at certain doses.

bioRxiv · Oct 30, 2024 · PreprintPharmacology & Toxicology