Potency, dissociation kinetics and reversibility of fentanyls and nitazenes by naloxone at the μ opioid receptor
Norah Alhosan, Damiana Cavallo, Marina Santiago, Eamonn Kelly, Graeme Henderson
This study compares the potency, dissociation kinetics, and naloxone antagonism of fentanyls and nitazenes at the μ opioid receptor, finding that slowly dissociating agonists are more resistant to naloxone.
British Journal of Pharmacology · Oct 22, 2024Peer-reviewedPharmacology & Toxicology