DeepVul: A Multi-Task Transformer Model for Joint Prediction of Gene Essentiality and Drug Response
Ala Jararweh, My Nguyen Bach, David Arredondo, Oladimeji Macaulay, Mikaela Dicome, Luis E. Tafoya, Yue Hu, Kushal Virupakshappa, Genevieve Marie Boland, Keith T. Flaherty, Avinash D Sahu
DeepVul predicts gene essentiality and drug response using a multi-task transformer model trained on cancer transcriptome data, improving precision oncology by identifying treatment vulnerabilities.
bioRxiv · Oct 17, 2024 · PreprintBioinformatics