Author

Lina M. Moreno

University of IowaORCID 0000-0002-9237-8179Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Eleanor FeingoldiD· 3 shared George L. WehbyiD· 3 shared Jacqueline T. HechtiD· 3 shared Mary L. MarazitaiD· 3 shared Seth Michael WeinbergiD· 3 shared Azeez ButaliiD· 2 shared Elizabeth J. LeslieiD· 2 shared Frederic W.‐B. DeleyiannisiD· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Eleanor FeingoldORCID

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3 papers

Recent·Most cited

Impact of low-frequency coding variants on human facial shape

Dongjing Liu, Nora Alhazmi, Harold S. Matthews, Myoung Keun Lee, Jiarui Li, Jacqueline T. Hecht, George L. Wehby, Lina M. Moreno, Carrie L. Heike, Jasmien Roosenboom, Eleanor Feingold, Mary L. Marazita, Peter D. Claes, Eric Chien-Wei Liao, Seth Michael Weinberg, John R. Shaffer

The paper investigates the impact of low-frequency coding variants on facial shape in Europeans, identifying seven genes associated with facial morphology and showing a specific variant's effect on chin shape.

Scientific Reports · Jan 12, 2021Peer-reviewedGenetics

Whole genome sequencing of orofacial cleft trios from the Gabriella Miller Kids First Pediatric Research Consortium identifies a new locus on chromosome 21

Nandita Mukhopadhyay, Madison R. Bishop, Michael Mortillo, Pankaj Chopra, Jacqueline B. Hetmanski, Margaret A. Taub, Lina M. Moreno, Luz Consuelo Valencia‐Ramirez, Claudia Restrepo, George L. Wehby, Jacqueline T. Hecht, Frederic W.‐B. Deleyiannis, Azeez Butali, Seth Michael Weinberg, Terri H. Beaty, , Mary L. Marazita

This study uses whole genome sequencing of OFC trios to identify a new locus on chromosome 21 associated with OFCs in Colombian families.

Human Genetics · Dec 17, 2019Peer-reviewedGenetics

A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals

Jenna C. Carlson, Deepti Anand, Azeez Butali, Carmen J. Buxó, Kaare Christensen, Frederic W.‐B. Deleyiannis, Jacqueline T. Hecht, Lina M. Moreno, Ieda Maria Orioli, Carmencita David Padilla, John R. Shaffer, Alexandre Rezende Vieira, George L. Wehby, Seth Michael Weinberg, Jeffrey Clark Murray, , Elizabeth J. Leslie

The paper develops a framework to analyze subtype-specific and shared genetic effects in orofacial clefting and applies it to identify loci associated with different subtypes.

Genetic Epidemiology · Jun 6, 2019Peer-reviewedGenetics