Beyond BRCA: Discovery of novel causes and consequences of homologous recombination deficiencies
Daniel James McGrail, Yang Li, Roger S. Smith, Bin Feng, Hui Dai, Yongsheng Li, Limei Hu, Briana K. Dennehey, Sharad Awasthi, Marc L. Mendillo, Gordon Brent Mills, Shiaw‐Yih Lin, S. Stephen Yi, Nidhi Sahni
This study identifies RNA binding proteins as novel drivers of homologous recombination deficiency in tumors, expanding the known genetic causes beyond BRCA1/2 mutations.
bioRxiv · Oct 1, 2022 · PreprintSystems Biology