Author

Simon M. Helfgott

Brigham and Women's HospitalORCID 0000-0002-9256-8052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Chamith Y. FonsekaiD· 1 shared Deepak A. RaoiD· 1 shared Derrick J. ToddiD· 1 shared Elena M. MassarottiiD· 1 shared Elizabeth W. KarlsoniD· 1 shared Ilya KorsunskyiD· 1 shared James A. Lederer· 1 shared Joerg ErmanniD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Chamith Y. FonsekaORCID

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1 paper

Recent·Most cited

Mixed Effects Association of Single Cells Identifies an Expanded Th1-Skewed Cytotoxic Effector CD4+ T Cell Subset in Rheumatoid Arthritis

Chamith Y. Fonseka, Deepak A. Rao, Nikola C. Teslovich, Ilya Korsunsky, Susan K. Hannes, Kamil Slowikowski, Michael F. Gurish, Laura T. Donlin, James A. Lederer, Michael E. Weinblatt, Elena M. Massarotti, Jonathan S. Coblyn, Simon M. Helfgott, Derrick J. Todd, Vivian P. Bykerk, , Soumya Raychaudhuri

The paper introduces MASC, a method to identify disease-associated cell subsets in single-cell data, and finds an expanded Th1-skewed cytotoxic CD4+ T cell subset in rheumatoid arthritis.

Science Translational Medicine · Oct 17, 2018Peer-reviewedBioinformatics