Author

Hui Chen

Shenzhen Bay LaboratoryORCID 0000-0002-9257-8728Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hui Chen10 papers · University of Illinois Chicago

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:GWAS / association mapping· 2 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Lei LiiD· 3 shared Xudong ZouiD· 3 shared Xuelian MaiD· 3 shared Lihai GongiD· 2 shared Ruofan DingiD· 2 shared Wenyan CheniD· 2 shared Xing LiiD· 2 shared Yangmei QiniD· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Lei LiORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintFeb 29, 2024

Enhancer RNA transcriptome-wide association study reveals an atlas of pan-cancer susceptibility eRNAs

Wenyan Chen, Zeyang Wang, Jianxiang Lin…·Lei Li

This study identifies eRNA-QTLs and susceptibility eRNAs across 23 cancer types, revealing new cancer susceptibility genes through eRNA-based transcriptome-wide association.

DOI 10.1101/2024.02.29.24303580

humanbulk RNA-seq

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedFeb 26, 2024

A distinct class of pan cancer susceptibility genes revealed by alternative polyadenylation transcriptome wide association study

Hui Chen, Zeyang Wang, Lihai Gong…·Lei Li

This study identifies 413 APA-linked cancer susceptibility genes by integrating GWAS data with APA quantification, showing genetic variants associated with APA explain a large portion of cancer heritability.

19 citations

humanbulk RNA-seq

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BioinformaticsBriefings in BioinformaticsPeer-reviewedNov 13, 2023

xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs

Ruofan Ding, Xudong Zou, Yangmei Qin…·Lei Li

xQTLbiolinks is a tool for integrative analysis of molecular QTLs, enabling retrieval, preprocessing, and colocalization with GWAS data to identify disease-risk genes.

26 citationstop 4%

humanGWAS summary statistics

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