Author

Urho M. Kujala

University of JyväskyläORCID 0000-0002-9262-1992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Eija K. LaakkoneniD· 2 shared Hanna‐Kaarina JuppiiD· 2 shared Sira M. KarvineniD· 2 shared Tero SieväneniD· 2 shared Tia-Marje K. KorhoneniD· 2 shared Aarno Palotie· 1 shared Adam E. Ziemann· 1 shared Anders MälarstigiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Eija K. LaakkonenORCID

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3 papers

Recent·Most cited

Menopausal transition alters female skeletal muscle transcriptome

Hanna‐Kaarina Juppi, Tia-Marje K. Korhonen, Tero Sievänen, Vuokko Kovanen, Urho M. Kujala, Pauliina Aukee, Neil J. Cronin, Sarianna Sipilä, Sira M. Karvinen, Eija K. Laakkonen

The paper examines how the menopausal transition affects the skeletal muscle transcriptome in women, identifying differentially expressed genes and regulatory networks linked to body composition changes.

Translational Exercise Biomedicine · Mar 12, 2024Peer-reviewedMolecular Biology

Extracellular vesicles and high-density lipoproteins: Exercise and estrogen-responsive small RNA carriers

Sira M. Karvinen, Tia-Marje K. Korhonen, Tero Sievänen, Jari E. Karppinen, Hanna‐Kaarina Juppi, Veera Jakoaho, Urho M. Kujala, Jari Antero Laukkanen, Maarit Lehti, Eija K. Laakkonen

The paper shows that extracellular vesicles and HDL particles have distinct small RNA content, and estrogen deficiency reduces exercise-induced miR responses in both.

Journal of Extracellular Vesicles · Feb 1, 2023Peer-reviewedMolecular Biology

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

Sanni Ruotsalainen, Juulia Partanen, Anna Cichońska, Jake Lin, Christian Benner, Ida L. Surakka, FinnGen, Aarno Palotie, Mark J. Daly, Pharmaceutical companies, Howard J. Jacob, Athena Matakidou, Heiko Runz, Sally John, Robert M. Plenge, , Kari Linden

The paper introduces a multivariate GWAS framework that identifies functional variants and disease associations by transforming multivariate results into univariate phenotypes for follow-up analysis.

European Journal of Human Genetics · Oct 27, 2020Peer-reviewedGenetics