Jari Antero Laukkanen

This study investigates the effects of xylo-oligosaccharide (XOS) prebiotic on hepatic steatosis in overweight individuals, finding that it reduces harmful gut metabolites and liver fat in responders.

This paper investigates associations between genetic and exogenous estrogen exposure and cardiovascular disease risk in women using GWAS and register-based hormone data.

This study identifies 1,242 novel genetic variants and 31 novel genes associated with frailty through genome-wide association and proteomics integration.

This study conducts a genome-wide meta-analysis across three biobanks to identify new genetic loci associated with lumbar disc herniation, expanding the known genetic landscape.

This study conducts a GWAS of preeclampsia and hypertensive disorders of pregnancy, identifying 18 genome-wide significant loci, including novel associations with blood pressure and placental function.

The paper shows that extracellular vesicles and HDL particles have distinct small RNA content, and estrogen deficiency reduces exercise-induced miR responses in both.

Finnish-enriched low-frequency variants, often coding, underlie many GWAS signals across 1,932 register endpoints in 218,792 Finns; a 15-disease meta-analysis with Estonian and UK biobanks adds 30 unreported associations.