BETA- AND GAMMA-SYNUCLEINS MODULATE SYNAPTIC VESICLE-BINDING OF ALPHA-SYNUCLEIN
Kathryn E. Carnazza, Lauren E. Komer, André Pineda, Yoonmi Na, Trudy F. Ramlall, Vladimir L. Buchman, David Eliezer, Manu Sharma, Jacqueline Burré
This study shows that beta-synuclein and gamma-synuclein modulate alpha-synuclein's membrane binding and synaptic function, but not its downstream roles in vesicle clustering and SNARE-complex assembly.
bioRxiv · Nov 19, 2020 · PreprintNeuroscience