Author

Vladimir L. Buchman

Russian Academy of SciencesORCID 0000-0002-7631-8352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Michail S. KukharskyiD· 2 shared Natalia N. NinkinaiD· 2 shared A. A. UstyugoviD· 1 shared Alexander P. RezvykhiD· 1 shared Alexey V. DeykiniD· 1 shared Ali ShaibiD· 1 shared André PinedaiD· 1 shared Camille Rabesahala de MeritensiD· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Michail S. KukharskyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity

Nanna Møller Jensen, YuHong Fu, Cristine Betzer, Hongyun Li, Sara Elfarrash, Ali Shaib, Donatus Krah, Zagorka Vitic, Lasse Reimer, Hjalte Gram, Vladimir L. Buchman, Mark Denham, Silvio O. Rizzoli, Glenda Margaret Halliday, Poul Henning Jensen

The paper introduces MJF-14 PLA, a proximity ligation assay for detecting non-inclusion alpha-synuclein aggregates with high specificity and sensitivity, showing pathology precedes Lewy body formation in Parkinson's disease.

npj Parkinson s Disease · Nov 29, 2024Peer-reviewedNeuroscience

BETA- AND GAMMA-SYNUCLEINS MODULATE SYNAPTIC VESICLE-BINDING OF ALPHA-SYNUCLEIN

Kathryn E. Carnazza, Lauren E. Komer, André Pineda, Yoonmi Na, Trudy F. Ramlall, Vladimir L. Buchman, David Eliezer, Manu Sharma, Jacqueline Burré

This study shows that beta-synuclein and gamma-synuclein modulate alpha-synuclein's membrane binding and synaptic function, but not its downstream roles in vesicle clustering and SNARE-complex assembly.

bioRxiv · Nov 19, 2020 · PreprintNeuroscience

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice

Michail S. Kukharsky, Natalia N. Ninkina, Haiyan An, Vsevolod Telezhkin, Wenbin Wei, Camille Rabesahala de Meritens, Johnathan Cooper‐Knock, Shinichi Nakagawa, Tetsuro Hirose, Vladimir L. Buchman, Tatyana A. Shelkovnikova

This study shows that NEAT1 regulates adaptive behavioural responses to stress in mice by affecting neuronal function and gene expression.

Translational Psychiatry · May 28, 2020Peer-reviewedNeuroscience

Low level of expression of C-terminally truncated human FUS causes extensive changes in spinal cord transcriptome of asymptomatic transgenic mice

Ekaterina A. Lysikova, S. Yu. Funikov, Alexander P. Rezvykh, Kirill Chaprov, Michail S. Kukharsky, A. A. Ustyugov, Alexey V. Deykin, Ilya M. Flyamer, Shelagh Boyle, Сергей Олегович Бачурин, Natalia N. Ninkina, Vladimir L. Buchman

The paper shows that low-level expression of a pathogenic C-terminally truncated FUS in mice causes transcriptome changes in the spinal cord without motor neuron pathology.

Neurochemical Research · Mar 11, 2020Peer-reviewedNeuroscience