Structure of Escherichia coli DNA gyrase with chirally wrapped DNA supports ratchet-and-pawl mechanism for an ATP-powered supercoiling motor
Elizabeth Michalczyk, Marta Pabiś, Jonathan G. Heddle, Dmitry Ghilarov
The paper presents cryoEM structures of Escherichia coli DNA gyrase with DNA loops, supporting a ratchet-and-pawl mechanism for ATP-powered supercoiling.
bioRxiv · Apr 12, 2024 · PreprintMolecular Biology