Author

Dmitry Ghilarov

John Innes CentreORCID 0000-0001-9325-3207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alena DrobiazkoiD· 1 shared Anna B. TrofimovaiD· 1 shared Artem B. IsaeviD· 1 shared Daria YatselenkoiD· 1 shared David M. LawsoniD· 1 shared Elizabeth MichalczykiD· 1 shared Jake RichardsoniD· 1 shared John W. PetersiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Alena DrobiazkoORCID

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3 papers

Recent·Most cited

MicrobiologyFEBS JournalPeer-reviewedSep 7, 2025

Structural analysis of the NifL-NifA complex reveals the molecular basis of anti-activation of nitrogen fixation gene expression in Azotobacter vinelandii

Marcelo Bueno Batista, Jake Richardson, Michael W. Webster…·Ray A. Dixon

The paper uses cryo-EM to study the NifL-NifA complex in Azotobacter vinelandii, revealing how NifL sequesters NifA to regulate nitrogen fixation and enabling engineered strains with enhanced nitrogen secretion.

3 citations

bacteria (other)cryo-EM

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Molecular BiologyNature CommunicationsPeer-reviewedFeb 20, 2025

Molecular basis of foreign DNA recognition by BREX anti-phage immunity system

Alena Drobiazko, Myfanwy C. Adams, Mikhail A. Skutel…·Artem B. Isaev

This study elucidates the molecular mechanism of BREX anti-phage immunity by showing how BrxX methyltransferase recognizes DNA and forms an immune complex to protect against phage infection.

28 citationstop 1%

E. coliDNA methylation

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Molecular BiologybioRxivPreprintApr 12, 2024

Structure of Escherichia coli DNA gyrase with chirally wrapped DNA supports ratchet-and-pawl mechanism for an ATP-powered supercoiling motor

Elizabeth Michalczyk, Marta Pabiś, Jonathan G. Heddle, Dmitry Ghilarov

The paper presents cryoEM structures of Escherichia coli DNA gyrase with DNA loops, supporting a ratchet-and-pawl mechanism for ATP-powered supercoiling.

5 citations

E. coliexperimental assay

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