Effects of prenatal maternal immune activation and exposure to circadian disruption during adolescence: exploring the two-hit model of neurodevelopmental disorders
Tara C. Delorme, Danusa Mar Arcego, Danae Penichet, Nicholas O’Toole, Nikki Huebener, Patrícia Pelufo Silveira, Lalit K. Srivastava, Nicolas Cermakian
This study investigates how prenatal maternal immune activation and adolescent circadian disruption interact to affect neurodevelopmental outcomes in mice, showing sex-specific behavioral and molecular effects.
bioRxiv · Feb 25, 2024 · PreprintNeuroscience