m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site
Matthew T Parker, Beth K Soanes, Jelena Kusakina, Antoine Larrieu, Katarzyna Knop, Nisha Joy, Friedrich Breidenbach, Anna V. Sherwood, Geoffrey J. Barton, Sebastian M. Fica, Brendan Davies, Gordon Grant Simpson
The paper shows that m6A modification of U6 snRNA affects splicing accuracy and efficiency, revealing two major classes of 5' splice sites in eukaryotes.
eLife · Nov 21, 2022Peer-reviewedMolecular Biology