Isoswitching in human brain development and aging
Beril Erdogdu, Hyun Joo Ji, Zoe Rudnick, Mihaela Pertea, Steven L. Salzberg
The paper identifies isoswitching, a phenomenon of isoform usage changes in human brain development and aging, and shows it can predict age across the lifespan using RNA-seq data.
bioRxiv · May 5, 2025 · PreprintGenomics