Sukhwan Park

Riboseek is a fast and sensitive sequence alignment tool for RNA and DNA that uses di-mers for alignment, outperforming BLASTN and nhmmer in speed and sensitivity.

Unicore identifies structural core genes for phylogenetic analysis using protein language models and structural strings, achieving faster runtime and broader taxonomic applicability than existing methods.

SoftAlign is an end-to-end protein structure alignment method that improves accuracy over existing tools while being compatible with other alignment strategies.

The paper investigates how multicopy gene families on the human Y chromosome survive despite lack of recombination, showing that homogenization via palindromes and arrays, along with purifying selection, preserve protein structure essential for fertility.

CHESS 3 improves upon previous versions by using better algorithms and filtering to create a more accurate catalog of human genes and transcripts.

The paper uses petabase-scale homology searches from SRA data to improve protein structure prediction accuracy using ColabFold, achieving better results than default methods.

The paper uses 3D protein structures to evaluate human protein isoforms for biological functionality, refining genome annotations.