Author

Hao Guo

Simcere Pharmaceutical (China)ORCID 0000-0002-9289-9775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:metagenomics· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Junfeng LiuiD· 2 shared Yong ReniD· 2 shared Bowen GaoiD· 1 shared Chengkun WuiD· 1 shared Chun Xia Song· 1 shared Haichuan Tan· 1 shared Ju GuiD· 1 shared Kelin Wu· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Junfeng LiuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GalaxyVS: Exploring 100-Billion Compounds in Seconds

Xin Hong, Peishun Li, Wenyu Zhu, Chengkun Wu, Hao Guo, Haichuan Tan, Qi Wu, Kelin Wu, Liangsheng Chen, Yinjun Jia, Bowen Gao, Xiaodong Jian, Zhiquan Lai, Youyou Lu, Xiangfei Meng, Yanyan Lan

GalaxyVS rapidly screens 100 billion compounds against protein structures, achieving high throughput and releasing a cross-species interaction database.

bioRxiv · Jun 3, 2026 · PreprintBioinformatics

ReDis: efficient metagenomic profiling via assigning ambiguous reads

Chun Xia Song, Zule Guo, Ju Gu, Yong Ren, Hao Guo, Junfeng Liu

ReDis improves metagenomic profiling accuracy by efficiently assigning ambiguous reads using a statistical model combined with Kraken2 and Minimap2.

bioRxiv · Aug 29, 2023 · PreprintBioinformatics

Centrifuge+: improving metagenomic analysis upon Centrifuge

Junfeng Liu, Runran Ma, Yong Ren, Hao Guo

Centrifuge+ improves metagenomic abundance estimation by addressing ambiguous reads through unique mapping rate, outperforming Centrifuge on simulated data.

bioRxiv · Feb 27, 2023 · PreprintBioinformatics