Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles
Xu Zheng, Shi Yu, Yanqiu Rachel Zhou, Kuai Yu, Yuhui Gao, Mengdan Chen, Dong Duan, Yunyi Li, Xiaoxian Cui, Jiabin Mou, Yuying Yang, Xun Wang, Min Chen, Yaming Jiu, Jincun Zhao, Guangxun Meng
The paper identifies IL-1β as a factor that inhibits SARS-CoV-2-induced cell-cell fusion by promoting actin bundles, thereby restricting viral transmission.
eLife · Feb 12, 2025Peer-reviewedImmunology