Author

Shuai Chen

Chinese Academy of SciencesORCID 0000-0002-9337-6191Unclaimed ORCID profile · follow to get notified of new preprints

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Shuai Chen1 paper

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Botai LiiD· 1 shared Chong QiniD· 1 shared Dan TengiD· 1 shared Dan Wang· 1 shared Dashuang GaoiD· 1 shared Fan YangiD· 1 shared Furong JuiD· 1 shared Guizhen Zhou· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Botai LiORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 28, 2026

Peri-Locus Coeruleus Controls Endothelial Cell Heterogeneity in Enriched Environments via Region-Specific Norepinephrine Signaling

Y ZHAO, Botai Li, Furong Ju…·Fan Yang

This study shows that peri-LC neurons regulate bone endothelial heterogeneity and density through norepinephrine signaling in enriched environments.

DOI 10.64898/2026.06.23.733358

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 12, 2026

Functional orthogonality of WRN inhibitor resistance enables alternating therapy and mutation-tolerant inhibitor design in MSI-H cancers

Guizhen Zhou, Dan Teng, Dan Wang…·Mingyue Zheng

This study shows that resistance to different WRN inhibitors in MSI-H cancers creates orthogonal vulnerabilities, enabling alternating therapy and mutation-tolerant inhibitor design.

DOI 10.64898/2026.06.09.731233

humanwhole-exome sequencing

𝕏 PostBluesky

Shuai Chen · henhao