A fluorescent non-hydrolyzable probe for the nucleotide binding sites of KATP
Priscilla Rubio, Sharon Whitaker, Jonathan Ashby, Michael C. Puljung
This paper develops a fluorescent ATP analog to study nucleotide binding sites on KATP channels, showing that non-hydrolyzable ATP analogs can bind to SUR1 sites and do not fail to activate KATP due to binding issues.
The Journal of General Physiology · Aug 21, 2026Peer-reviewedBiophysics